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COX-two/PGE2 pathway is improved in murine and human diabetic monocytes/macrophages. Unsuitable PGE2 exercise could preserve the inflammatory phenotype of wound macrophages, which isn't conducive on the fix of diabetic wounds 37. The duality of PGE2 along with the complexity of the human body need us to explore a lot more to find the higher therape
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, et al Identification of a household of cAMP reaction element-binding protein coactivators by genome-scale practical Examination in mammalian cells, et al Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-kappa B signal pathwaysCytochalasi